Optic atrophy type 1 is an autosomal dominant genetic disorder caused by mutations within the OPA1 gene [1]. The OPA1 gene can be found mainly in the retinal ganglion cells [2]. Mutations in the OPA1 gene disrupt normal protein production and lead to altered mitochondrial structure [3]. This mitochondrial dysfunction triggers apoptosis in optic nerve cells, impairs synaptic transport, and ultimately results in optic atrophy type 1 [5]. Based on recent studies, it is known that optic atrophy type 1 patients suffer from blindness, blocked vision, or color vision deficiency [4].
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