A protein-protein interaction network (PPI) is a scientific approach for researchers to find disease-related proteins from the reactions between genes with similar functions [1]. The network combined the epigenetic characteristics of the gene and aids in drug discovery by identifying new pathways. The database used for graphs generated on this webpage is STRING, based on data from existing databases and past experiments. Some other protein interaction network databases are: IntAct, BioGrid, Panther.
known OPA1 PROTEIN INTERACTION NETWORK in human & zebrafish
OPA1 interaction network in human
OPA1 interaction network in zebrafish
DISCUSSION
There are similar proteins shown in both interaction networks. Both of them have proteins responsible for synapse transport and mitochondria protein-containing complex, but zebrafish is missing the protein that responsible for GTP binding. This study aimed to study the function of mitochondria, so the interaction networks have validate that zebrafish is a great model organism of this study.
This web page was produced as an assignment for Genetics 564, a capstone course at UW-Madison. Dianna Xie | [email protected] | Last updated 05/09/2024